ACL Top 550 CTS

ACL TOP 550

Applications

Anticoagulation Therapy Monitoring:

  • The ACL TOP 550 is ideal for monitoring patients on anticoagulants such as warfarin, heparin, and direct oral anticoagulants (DOACs), particularly through Anti-Xa assays, which are used to monitor heparin therapy and Factor Xa inhibitors.
  • The system provides fast, reliable results to help clinicians adjust medication dosages and maintain patients within safe therapeutic ranges.

Bleeding Disorder Diagnosis:

  • It is widely used for the diagnosis and management of bleeding disorders, including hemophilia, von Willebrand disease, liver disease, and other conditions related to coagulation factor deficiencies. The analyzer provides tests such as Factor VIII, Factor IX, von Willebrand factor, and Fibrinogen.

Thrombophilia Screening:

  • The ACL TOP 550 is used for screening patients for thrombophilia, a condition characterized by an increased tendency to form blood clots. The analyzer supports tests such as Factor V Leiden mutation testing, prothrombin gene mutation, and protein C and S deficiencies.

Surgical Monitoring:

  • It is used in preoperative assessments and surgical monitoring, especially in cardiothoracic surgery, orthopedic surgery, and neurosurgery, where precise management of coagulation is critical to avoid bleeding or thrombosis.

Critical Care and Emergency Medicine:

  • The ACL TOP 550 is suitable for use in emergency departments, ICUs, and other critical care settings, where rapid coagulation testing is essential for managing trauma patients, sepsis, shock, and other life-threatening conditions requiring immediate intervention.

Technical Specifications:

Throughput: Up to 400 tests per hour.

Sample Types: Plasma, whole blood, serum.

Test Types: PT, APTT, INR, Fibrinogen, D-dimer, Anti-Xa, Factor assays, Platelet function tests, Thrombophilia screening.

Sample Capacity: Can process up to 30 samples simultaneously.

Reagents: Liquid reagents and reagent discs.

Display: High-resolution touchscreen with color-coded results and graphical trend analysis.

Data Connectivity: Integration with LIS, HIS, and EMR systems.

Quality Control: Automatic internal QC and external QC options.

Calibration: Automated calibration and self-checking features.

Safety Features: Sample integrity checks, biohazard protection, automated cleaning cycles.

Dimensions: Compact design for high-throughput labs.

Product Description

The ACL TOP 550 is a high-performance coagulation analyzer from Werfen, designed for high-volume clinical laboratories requiring rapid, accurate, and reliable testing of hemostasis and coagulation profiles. Part of the ACL TOP series, the ACL TOP 550 combines advanced technology with user-friendly automation to deliver fast results for a wide range of coagulation tests, including routine and specialized assays for monitoring blood coagulation, bleeding and clotting disorders, and anticoagulant therapy. This analyzer is ideal for hospitals, reference laboratories, and other high-demand environments where efficiency, flexibility, and accuracy are paramount.

Key Features:

  • Comprehensive Coagulation Testing Menu: The ACL TOP 550 supports a broad spectrum of coagulation tests, including:
    • Prothrombin Time (PT)
    • Activated Partial Thromboplastin Time (APTT)
    • International Normalized Ratio (INR)
    • Fibrinogen levels
    • D-dimer
    • Thrombin Time (TT)
    • Anti-Xa assays (for heparin monitoring)
    • Factor assays (e.g., Factor VIII, Factor IX, Factor II)
    • Platelet function tests (including platelet aggregation and adhesion)
    • Thrombophilia screening (Factor V Leiden, prothrombin mutation)
    These capabilities make it suitable for monitoring anticoagulant therapy, diagnosing bleeding disorders (like hemophilia), and identifying thrombophilia (the tendency to form abnormal clots).
  • High Throughput with Fast Turnaround Times:
    • The ACL TOP 550 offers an impressive throughput of up to 400 tests per hour, making it ideal for high-volume laboratories with heavy coagulation testing loads.
    • The analyzer features rapid test processing, with results typically available in less than 5 minutes per test, ensuring quick decision-making in time-sensitive clinical situations.
  • Automated Sample Processing and Carousel:
    • The ACL TOP 550 is equipped with an automated sample loading carousel, which can hold multiple patient samples and processes them simultaneously, increasing productivity and reducing the need for manual intervention.
    • The system allows for continuous sample loading and can process up to 30 samples at a time, making it ideal for environments with high test volumes.
  • User-Friendly Interface:
    • The analyzer features a large touchscreen interface, designed to provide clear, easy-to-read displays of results, trend analysis, and test options.
    • Color-coded results and graphical representations (e.g., histograms and trend graphs) allow laboratory professionals to quickly interpret coagulation data.
    • One-touch operations for test selection and result viewing enhance workflow and reduce user error.
  • Advanced Quality Control (QC) and Calibration:
    • The ACL TOP 550 is equipped with automatic quality control (QC), including internal QC and calibration checks, ensuring consistent and accurate test results.
    • The system runs automated internal quality controls after every set of tests and provides alerts if results are outside acceptable ranges.
    • It also supports external QC, meeting regulatory standards such as CAP (College of American Pathologists) and CLIA (Clinical Laboratory Improvement Amendments).
  • Multiple Sample Types:
    • The analyzer is capable of processing a variety of sample types, including plasma, whole blood, and serum, providing flexibility depending on the laboratory's testing requirements.
    • It accommodates multiple reagent types, including liquid reagents and reagent discs, allowing labs to optimize reagent usage based on their specific needs.
  • Advanced Data Management and Connectivity:
    • The ACL TOP 550 features comprehensive data management and connectivity capabilities, enabling integration with Laboratory Information Systems (LIS), Hospital Information Systems (HIS), and Electronic Medical Records (EMR) systems.
    • It allows for real-time data transfer, result trending, and easy access to patient test histories, supporting efficient workflow and reducing the risk of errors.
    • Test results and data can be easily printed or exported for further analysis and interpretation.
  • Built-in Safety Features:
    • The ACL TOP 550 includes built-in sample integrity checks, which ensure that the sample quality is suitable for testing (checking for common issues such as hemolysis, clotting, or insufficient sample volume).
    • Biohazard protection and automated system cleaning cycles ensure safe handling of patient samples and minimize the risk of contamination.
  • Cost-Effective Operation:
    • The analyzer's efficient reagent usage and automated maintenance features help reduce operational costs and downtime.
    • Flexible reagent options, including liquid reagents and reagent discs, allow laboratories to optimize reagent inventory and minimize waste.